MGP Database

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MGP001936

Ontology/Pathway Information

Entrez Gene ID4313
Gene Namematrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
Gene Symbol MMP2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:BHF-UCLCextracellular space
GO:0005739 IEA:UniProtKB-SubCellCmitochondrion
GO:0005634 IEA:UniProtKB-SubCellCnucleus
GO:0005886 IEA:EnsemblCplasma membrane
GO:0005578 IEA:UniProtKB-SubCellCproteinaceous extracellular matrix
GO:0030017 IEA:EnsemblCsarcomere
GO:0004222 TAS:ProtIncFmetalloendopeptidase activity
GO:0004252 TAS:ReactomeFserine-type endopeptidase activity
GO:0008270 TAS:ProtIncFzinc ion binding
GO:0001525 IEA:UniProtKB-KWPangiogenesis
GO:0001955 IEA:EnsemblPblood vessel maturation
GO:0060346 IEA:EnsemblPbone trabecula formation
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0071230 IEA:EnsemblPcellular response to amino acid stimulus
GO:0030574 TAS:ReactomePcollagen catabolic process
GO:0007566 IEA:EnsemblPembryo implantation
GO:0035987 IEP:UniProtKBPendodermal cell differentiation
GO:0022617 TAS:ReactomePextracellular matrix disassembly
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0060325 IEA:EnsemblPface morphogenesis
GO:0001957 IEA:EnsemblPintramembranous ossification
GO:0045089 IEA:EnsemblPpositive regulation of innate immune response
GO:0006508 IDA:ParkinsonsUK-UCLPproteolysis
GO:0001666 IEA:EnsemblPresponse to hypoxia
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_118682Activation of Matrix Metalloproteinases
REACT_18266Axon guidance
REACT_150401Collagen degradation
REACT_118572Degradation of the extracellular matrix
REACT_111045Developmental Biology
REACT_264198EPH-ephrin mediated repulsion of cells
REACT_264068EPH-Ephrin signaling
REACT_118779Extracellular matrix organization
REACT_17015Metabolism of proteins
REACT_15428Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
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