MGP Database

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MGP001961

Ontology/Pathway Information

Entrez Gene ID4363
Gene NameATP-binding cassette, sub-family C (CFTR/MRP), member 1
Gene Symbol ABCC1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0016020 IDA:UniProtKBCmembrane
GO:0005886 IDA:HPACplasma membrane
GO:0016887 IDA:UniProtKBFATPase activity
GO:0042626 TAS:ProtIncFATPase activity, coupled to transmembrane movement of substances
GO:0005524 TAS:ProtIncFATP binding
GO:0005215 TAS:ProtIncFtransporter activity
GO:0019369 TAS:ReactomeParachidonic acid metabolic process
GO:0006200 IDA:GOCPATP catabolic process
GO:0009235 TAS:ReactomePcobalamin metabolic process
GO:0006691 TAS:ReactomePleukotriene metabolic process
GO:0042493 TAS:ProtIncPresponse to drug
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0055085 TAS:ReactomePtransmembrane transport
GO:0006810 TAS:ProtIncPtransport
GO:0006766 TAS:ReactomePvitamin metabolic process
GO:0006767 TAS:ReactomePwater-soluble vitamin metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15480ABC-family proteins mediated transport
REACT_147851Arachidonic acid metabolism
REACT_163862Cobalamin (Cbl, vitamin B12) transport and metabolism
REACT_169280Defective AMN causes hereditary megaloblastic anemia 1
REACT_169403Defective BTD causes biotidinase deficiency
REACT_169178Defective CD320 causes methylmalonic aciduria
REACT_169132Defective CUBN causes hereditary megaloblastic anemia 1
REACT_169415Defective GIF causes intrinsic factor deficiency
REACT_169312Defective HLCS causes multiple carboxylase deficiency
REACT_169363Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
REACT_169316Defective MMAA causes methylmalonic aciduria type cblA
REACT_169318Defective MMAB causes methylmalonic aciduria type cblB
REACT_169169Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
REACT_169256Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
REACT_169149Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
REACT_169439Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
REACT_169313Defective MUT causes methylmalonic aciduria mut type
REACT_169120Defective TCN2 causes hereditary megaloblastic anemia
REACT_169238Defects in biotin (Btn) metabolism
REACT_169429Defects in cobalamin (B12) metabolism
REACT_169385Defects in vitamin and cofactor metabolism
REACT_116125Disease
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_11193Metabolism of vitamins and cofactors
REACT_11238Metabolism of water-soluble vitamins and cofactors
REACT_150420Synthesis of Leukotrienes (LT) and Eoxins (EX)
REACT_15518Transmembrane transport of small molecules
SMP Pathway Links
SMP IDDescription
SMP00640Acetaminophen Metabolism Pathway
SMP00435Docetaxel Action Pathway
SMP00650Doxorubicin Metabolism Pathway
SMP00433Irinotecan Action Pathway
SMP00600Irinotecan Metabolism Pathway
SMP00649Lamivudine Metabolism Pathway
SMP00434Paclitaxel Action Pathway
SMP00436Vinblastine Action Pathway
SMP00437Vincristine Action Pathway
SMP00438Vindesine Action Pathway
SMP00439Vinorelbine Action Pathway
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