MGP Database

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MGP002017

Ontology/Pathway Information

Entrez Gene ID4638
Gene Namemyosin light chain kinase
Gene Symbol MYLK
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005911 IEA:EnsemblCcell-cell junction
GO:0032154 IDA:UniProtKBCcleavage furrow
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0030027 IDA:UniProtKBClamellipodium
GO:0001725 IDA:UniProtKBCstress fiber
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004683 IBA:GO_CentralFcalmodulin-dependent protein kinase activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004687 IDA:UniProtKBFmyosin light chain kinase activity
GO:0007015 IBA:GO_CentralPactin filament organization
GO:0060414 IMP:BHF-UCLPaorta smooth muscle tissue morphogenesis
GO:0032060 IMP:UniProtKBPbleb assembly
GO:0071476 IDA:UniProtKBPcellular hypotonic response
GO:0006936 TAS:ReactomePmuscle contraction
GO:0051928 IDA:UniProtKBPpositive regulation of calcium ion transport
GO:0030335 IDA:UniProtKBPpositive regulation of cell migration
GO:0090303 IDA:UniProtKBPpositive regulation of wound healing
GO:0006468 TAS:ProtIncPprotein phosphorylation
GO:0006939 ISS:UniProtKBPsmooth muscle contraction
GO:0014820 ISS:UniProtKBPtonic smooth muscle contraction
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_17044Muscle contraction
REACT_20558Smooth Muscle Contraction
SMP Pathway Links
SMP IDDescription
SMP00296Acebutolol Action Pathway
SMP00297Alprenolol Action Pathway
SMP00665Amiodarone Action Pathway
SMP00376Amlodipine Action Pathway
SMP00664Arbutamine Action Pathway
SMP00298Atenolol Action Pathway
SMP00299Betaxolol Action Pathway
SMP00668Bevantolol Action Pathway
SMP00300Bisoprolol Action Pathway
SMP00657Bopindolol Action Pathway
SMP00670Bupranolol Action Pathway
SMP00658Carteolol Action Pathway
SMP00367Carvedilol Action Pathway
SMP00359Diltiazem Action Pathway
SMP00325Disopyramide Action Pathway
SMP00662Dobutamine Action Pathway
SMP00661Epinephrine Action Pathway
SMP00301Esmolol Action Pathway
SMP00377Felodipine Action Pathway
SMP00331Flecainide Action Pathway
SMP00326Fosphenytoin (Antiarrhythmic) Action Pathway
SMP00332Ibutilide Action Pathway
SMP00354Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin
SMP00663Isoprenaline Action Pathway
SMP00378Isradipine Action Pathway
SMP00368Labetalol Action Pathway
SMP00666Levobunolol Action Pathway
SMP00328Lidocaine (Antiarrhythmic) Action Pathway
SMP00667Metipranolol Action Pathway
SMP00302Metoprolol Action Pathway
SMP00329Mexiletine Action Pathway
SMP00588Muscle/Heart Contraction
SMP00303Nadolol Action Pathway
SMP00366Nebivolol Action Pathway
SMP00379Nifedipine Action Pathway
SMP00380Nimodipine Action Pathway
SMP00381Nisoldipine Action Pathway
SMP00382Nitrendipine Action Pathway
SMP00304Oxprenolol Action Pathway
SMP00305Penbutolol Action Pathway
SMP00327Phenytoin (Antiarrhythmic) Action Pathway
SMP00306Pindolol Action Pathway
SMP00669Practolol Action Pathway
SMP00324Procainamide (Antiarrhythmic) Action Pathway
SMP00307Propranolol Action Pathway
SMP00323Quinidine Action Pathway
SMP00660Sotalol Action Pathway
SMP00659Timolol Action Pathway
SMP00330Tocainide Action Pathway
SMP00375Verapamil Action Pathway
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