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MGP002064

Record overview

MGPD IDMGP002064
Gene ID4722
SpeciesHomo sapiens (Human)
Gene NameNADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
Gene Symbol NDUFS3
SynonymsCI-30;
Alternate namesNADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; CI-30kD; NADH dehydrogenase-ubiquinone 30 kDa subunit; NADH-ubiquinone oxidoreductase 30 kDa subunit; complex I 30kDa subunit; complex I-30kD;
Chromosome11
Map Location11p11.11
EC Number1.6.5.3
SummaryThis gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009]
OrthologsView orthologs and multiple alignments for NDUFS3

Proteins

NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial precursor
Refseq ID:NP_004542
Protein GI:4758788
UniProt ID:O75489
mRNA ID:NM_004551
Length:264
RefSeq Status:
MAAAAVARLWWRGILGASALTRGTGRPSVLLLPVRRESAGADTRPTVRPRNDVAHKQLSAFGEYVAEILPKYVQQVQVSCFNELEVCIHPDGVIPVLTFL
RDHTNAQFKSLVDLTAVDVPTRQNRFEIVYNLLSLRFNSRIRVKTYTDELTPIESAVSVFKAANWYEREIWDMFGVFFANHPDLRRILTDYGFEGHPFRK
DFPLSGYVELRYDDEVKRVVAEPVELAQEFRKFDLNSPWEAFPVYRQPPESLKLEAGDKKPDAK
 
transit_peptide: 1..36
calculated_mol_wt: 3845
peptide sequence: 
MAAAAVARLWWRGILGASALTRGTGRPSVLLLPVRR

mat_peptide: 37..264
product: NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
calculated_mol_wt: 26415
peptide sequence: 
ESAGADTRPTVRPRNDVAHKQLSAFGEYVAEILPKYVQQVQVSCFNELEVCIHPDGVIPVLTFLRDHTNAQFKSLVDLTAVDVPTRQNRFEIVYNLLSLR
FNSRIRVKTYTDELTPIESAVSVFKAANWYEREIWDMFGVFFANHPDLRRILTDYGFEGHPFRKDFPLSGYVELRYDDEVKRVVAEPVELAQEFRKFDLN
SPWEAFPVYRQPPESLKLEAGDKKPDAK
 
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