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MGP002126

Record overview

MGPD IDMGP002126
Gene ID4886
SpeciesHomo sapiens (Human)
Gene Nameneuropeptide Y receptor Y1
Gene Symbol NPY1R
SynonymsNPYR; NPY1-R;
Alternate namesneuropeptide Y receptor type 1;
Chromosome4
Map Location4q31.3-q32
SummaryThis gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013]
OrthologsView orthologs and multiple alignments for NPY1R

Proteins

neuropeptide Y receptor type 1
Refseq ID:NP_000900
Protein GI:4505445
UniProt ID:P25929
mRNA ID:NM_000909
Length:384
RefSeq Status:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVY
TLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFD
QFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNL
LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
 
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