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MGP002133

Record overview

MGPD IDMGP002133
Gene ID4902
SpeciesHomo sapiens (Human)
Gene Nameneurturin
Gene Symbol NRTN
SynonymsNTN;
Alternate namesneurturin; prepro-neurturin;
Chromosome19
Map Location19p13.3
SummaryNeurturin is a member of the TGF-beta subfamily, TRN. This gene signals through RET and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for NRTN

Proteins

neurturin preproprotein
Refseq ID:NP_004549
Protein GI:4758826
UniProt ID:Q99748
mRNA ID:NM_004558
Length:197
RefSeq Status:
MQRWKAAALASVLCSSVLSIWMCREGLLLSHRLGPALVPLHRLPRTLDARIARLAQYRALLQGAPDAMELRELTPWAGRPPGPRRRAGPRRRRARARLGA
RPCGLRELEVRVSELGLGYASDETVLFRYCAGACEAAARVYDLGLRRLRQRRRLRRERVRAQPCCRPTAYEDEVSFLDAHSRYHTVHELSARECACV
 
sig_peptide: 1..19
calculated_mol_wt: 2021
peptide sequence: 
MQRWKAAALASVLCSSVLS

mat_peptide: 96..197
product: neurturin
calculated_mol_wt: 11684
peptide sequence: 
ARLGARPCGLRELEVRVSELGLGYASDETVLFRYCAGACEAAARVYDLGLRRLRQRRRLRRERVRAQPCCRPTAYEDEVSFLDAHSRYHTVHELSARECA
CV
 
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