MGP Database

MGP002157

Record overview

MGPD ID	MGP002157
Gene ID	4969
Species	Homo sapiens (Human)
Gene Name	osteoglycin
Gene Symbol	OGN
Synonyms	OG; OIF; SLRR3A;
Alternate names	mimecan; corneal keratan sulfate proteoglycan; mimecan proteoglycan; osteoinductive factor;
Chromosome	9
Map Location	9q22
Summary	This gene encodes a protein which induces ectopic bone formation in conjunction with transforming growth factor beta. This protein is a small proteoglycan which contains tandem leucine-rich repeats (LRR). Alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Orthologs	View orthologs and multiple alignments for OGN

Proteins

mimecan preproprotein

Refseq ID:	NP_148935
Protein GI:	14916498
UniProt ID:	P20774
mRNA ID:	NM_033014
Length:	298
RefSeq Status:

`MKTLQSTLLLLLLVPLIKPAPPTQQDSRIIYDYGTDNFEESIFSQDYEDKYLDGKNIKEKETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCL SGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIK SRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF`

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2135
peptide sequence: 
MKTLQSTLLLLLLVPLIKP

mat_peptide: 194..298
product: mimecan
calculated_mol_wt: 12034
peptide sequence: 
AKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLP
IGSYF

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2135
peptide sequence: 
MKTLQSTLLLLLLVPLIKP

mat_peptide: 194..298
product: mimecan
calculated_mol_wt: 12034
peptide sequence: 
AKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLP
IGSYF

mimecan preproprotein

Refseq ID:	NP_054776
Protein GI:	7661704
UniProt ID:	P20774
mRNA ID:	NM_014057
Length:	298
RefSeq Status:

Protein sequence is identical to GI:14916498 (mRNA isoform)

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2135
peptide sequence: 
MKTLQSTLLLLLLVPLIKP

mat_peptide: 194..298
product: mimecan
calculated_mol_wt: 12034
peptide sequence: 
AKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLP
IGSYF