MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP002189

Ontology/Pathway Information

Entrez Gene ID5034
Gene Nameprolyl 4-hydroxylase, beta polypeptide
Gene Symbol P4HB
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005783 IDA:BHF-UCLCendoplasmic reticulum
GO:0005793 IDA:UniProtKBCendoplasmic reticulum-Golgi intermediate compartment
GO:0005788 TAS:ReactomeCendoplasmic reticulum lumen
GO:0005576 NAS:UniProtKBCextracellular region
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0042470 IEA:UniProtKB-SubCellCmelanosome
GO:0005886 IEA:UniProtKB-SubCellCplasma membrane
GO:0016222 IDA:MGICprocollagen-proline 4-dioxygenase complex
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0004656 TAS:ProtIncFprocollagen-proline 4-dioxygenase activity
GO:0003756 IBA:GO_CentralFprotein disulfide isomerase activity
GO:0045454 IEA:InterProPcell redox homeostasis
GO:0071456 IMP:BHF-UCLPcellular response to hypoxia
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0042157 TAS:ReactomePlipoprotein metabolic process
GO:0018401 IDA:MGIPpeptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0006457 IBA:GO_CentralPprotein folding
GO:1902175 IMP:BHF-UCLPregulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:0034976 IMP:BHF-UCLPresponse to endoplasmic reticulum stress
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_120956Cellular responses to stress
REACT_6841Chylomicron-mediated lipid transport
REACT_121139Collagen biosynthesis and modifying enzymes
REACT_120729Collagen formation
REACT_264249Detoxification of Reactive Oxygen Species
REACT_116125Disease
REACT_118779Extracellular matrix organization
REACT_264605Hedgehog ligand biogenesis
REACT_602Lipid digestion, mobilization, and transport
REACT_6823Lipoprotein metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_264623Processing-defective Hh variants abrogate ligand secretion
REACT_264508Signaling by Hedgehog
REACT_111102Signal Transduction
  logo