MGP Database

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MGP002191

Ontology/Pathway Information

Entrez Gene ID5046
Gene Nameproprotein convertase subtilisin/kexin type 6
Gene Symbol PCSK6
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:BHF-UCLCcell surface
GO:0005783 IEA:UniProtKB-SubCellCendoplasmic reticulum
GO:0031012 IDA:BHF-UCLCextracellular matrix
GO:0005615 IDA:BHF-UCLCextracellular space
GO:0005796 TAS:ReactomeCGolgi lumen
GO:0016020 IEA:UniProtKB-KWCmembrane
GO:0004175 IDA:BHF-UCLFendopeptidase activity
GO:0008201 IDA:BHF-UCLFheparin binding
GO:0048406 IDA:BHF-UCLFnerve growth factor binding
GO:0004252 IDA:BHF-UCLFserine-type endopeptidase activity
GO:0007368 IEA:EnsemblPdetermination of left/right symmetry
GO:0009100 IDA:BHF-UCLPglycoprotein metabolic process
GO:0032455 TAS:ReactomePnerve growth factor processing
GO:0032902 IDA:BHF-UCLPnerve growth factor production
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0016486 IDA:BHF-UCLPpeptide hormone processing
GO:0016485 IDA:BHF-UCLPprotein processing
GO:0030510 TAS:BHF-UCLPregulation of BMP signaling pathway
GO:0032940 IDA:BHF-UCLPsecretion by cell
GO:0007354 IEA:EnsemblPzygotic determination of anterior/posterior axis, embryo
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111045Developmental Biology
REACT_11062NGF processing
REACT_111057Signaling by NODAL
REACT_11061Signalling by NGF
REACT_111102Signal Transduction
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