MGP Database

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MGP002192

Ontology/Pathway Information

Entrez Gene ID5048
Gene Nameplatelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
Gene Symbol PAFAH1B1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0000235 IDA:UniProtKBCastral microtubule
GO:0030424 IEA:EnsemblCaxon
GO:0005938 IDA:UniProtKBCcell cortex
GO:0031252 IEA:EnsemblCcell leading edge
GO:0005813 IDA:UniProtKBCcentrosome
GO:0005829 ISS:BHF-UCLCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0030426 IEA:EnsemblCgrowth cone
GO:0005871 IEA:EnsemblCkinesin complex
GO:0000776 IDA:UniProtKBCkinetochore
GO:0005875 IDA:UniProtKBCmicrotubule associated complex
GO:0031512 ISS:BHF-UCLCmotile primary cilium
GO:0043025 IEA:EnsemblCneuronal cell body
GO:0005635 IDA:UniProtKBCnuclear envelope
GO:0031965 IEA:UniProtKB-SubCellCnuclear membrane
GO:0048471 ISS:BHF-UCLCperinuclear region of cytoplasm
GO:0034452 ISS:BHF-UCLFdynactin binding
GO:0045502 IDA:UniProtKBFdynein binding
GO:0008201 ISS:BHF-UCLFheparin binding
GO:0008017 ISS:BHF-UCLFmicrotubule binding
GO:0043274 ISS:BHF-UCLFphospholipase binding
GO:0051219 ISS:BHF-UCLFphosphoprotein binding
GO:0042803 ISS:BHF-UCLFprotein homodimerization activity
GO:0001675 ISS:BHF-UCLPacrosome assembly
GO:0030036 ISS:BHF-UCLPactin cytoskeleton organization
GO:0008344 IMP:BHF-UCLPadult locomotory behavior
GO:0001667 IEA:EnsemblPameboidal-type cell migration
GO:0048854 IMP:BHF-UCLPbrain morphogenesis
GO:0021987 IMP:BHF-UCLPcerebral cortex development
GO:0021895 IEA:EnsemblPcerebral cortex neuron differentiation
GO:0021540 IMP:BHF-UCLPcorpus callosum morphogenesis
GO:0051660 IEA:EnsemblPestablishment of centrosome localization
GO:0000132 IMP:UniProtKBPestablishment of mitotic spindle orientation
GO:0000086 TAS:ReactomePG2/M transition of mitotic cell cycle
GO:0021766 ISS:BHF-UCLPhippocampus development
GO:0021819 ISS:BHF-UCLPlayer formation in cerebral cortex
GO:0007611 ISS:BHF-UCLPlearning or memory
GO:0016042 IEA:UniProtKB-KWPlipid catabolic process
GO:0007017 IDA:UniProtKBPmicrotubule-based process
GO:0000226 ISS:BHF-UCLPmicrotubule cytoskeleton organization
GO:0031023 IMP:UniProtKBPmicrotubule organizing center organization
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0007067 IEA:UniProtKB-KWPmitotic nuclear division
GO:0046329 IEA:EnsemblPnegative regulation of JNK cascade
GO:0010977 IEA:EnsemblPnegative regulation of neuron projection development
GO:0007405 ISS:BHF-UCLPneuroblast proliferation
GO:0050885 IMP:BHF-UCLPneuromuscular process controlling balance
GO:0001764 IMP:UniProtKBPneuron migration
GO:0051081 IEA:EnsemblPnuclear envelope disassembly
GO:0007097 IEA:EnsemblPnuclear migration
GO:0036035 IEA:EnsemblPosteoclast development
GO:0046469 ISS:BHF-UCLPplatelet activating factor metabolic process
GO:0045773 IEA:EnsemblPpositive regulation of axon extension
GO:0001961 IEA:EnsemblPpositive regulation of cytokine-mediated signaling pathway
GO:0045931 IEA:EnsemblPpositive regulation of mitotic cell cycle
GO:0009306 IEA:EnsemblPprotein secretion
GO:0032319 ISS:BHF-UCLPregulation of Rho GTPase activity
GO:0008090 ISS:BHF-UCLPretrograde axon cargo transport
GO:0017145 IEA:EnsemblPstem cell division
GO:0007268 ISS:BHF-UCLPsynaptic transmission
GO:0019226 ISS:BHF-UCLPtransmission of nerve impulse
GO:0047496 ISS:BHF-UCLPvesicle transport along microtubule
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_267965Anchoring of the basal body to the plasma membrane
REACT_268265Assembly of the primary cilium
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_15479Centrosome maturation
REACT_2203G2/M Transition
REACT_15364Loss of Nlp from mitotic centrosomes
REACT_15451Loss of proteins required for interphase microtubule organization from the centrosome
REACT_1275Mitotic Anaphase
REACT_21391Mitotic G2-G2/M phases
REACT_150314Mitotic Metaphase and Anaphase
REACT_682Mitotic Prometaphase
REACT_910M Phase
REACT_264135Organelle biogenesis and maintenance
REACT_15296Recruitment of mitotic centrosome proteins and complexes
REACT_160315Regulation of PLK1 Activity at G2/M Transition
REACT_150425Resolution of Sister Chromatid Cohesion
REACT_150471Separation of Sister Chromatids
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