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MGP002193

Record overview

MGPD IDMGP002193
Gene ID5052
SpeciesHomo sapiens (Human)
Gene Nameperoxiredoxin 1
Gene Symbol PRDX1
SynonymsPAG; PAGA; PAGB; PRX1; PRXI; MSP23; NKEFA; TDPX2; NKEF-A;
Alternate namesperoxiredoxin-1; natural killer cell-enhancing factor A; natural killer-enhancing factor A; proliferation-associated gene A; proliferation-associated gene protein; thioredoxin peroxidase 2; thioredoxin-dependent peroxide reductase 2;
Chromosome1
Map Location1p34.1
EC Number1.11.1.15
SummaryThis gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011]
OrthologsView orthologs and multiple alignments for PRDX1

Proteins

peroxiredoxin-1
Refseq ID:NP_001189360
Protein GI:320461711
UniProt ID:Q06830
mRNA ID:NM_001202431
Length:199
RefSeq Status:
MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPM
NIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK
 
peroxiredoxin-1
Refseq ID:NP_859048
Protein GI:32455266
UniProt ID:Q06830
mRNA ID:NM_181697
Length:199
RefSeq Status:
Protein sequence is identical to GI:320461711 (mRNA isoform)
 
peroxiredoxin-1
Refseq ID:NP_859047
Protein GI:32455264
UniProt ID:Q06830
mRNA ID:NM_181696
Length:199
RefSeq Status:
Protein sequence is identical to GI:320461711 (mRNA isoform)
 
peroxiredoxin-1
Refseq ID:NP_002565
Protein GI:4505591
UniProt ID:Q06830
mRNA ID:NM_002574
Length:199
RefSeq Status:
Protein sequence is identical to GI:320461711 (mRNA isoform)
 
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