MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP002196

UniProt Annotations

Entry Information
Gene Nameserpin peptidase inhibitor, clade B (ovalbumin), member 2
Protein EntryPAI2_HUMAN
UniProt IDP05120
SpeciesHuman
Comments
Comment typeDescription
FunctionInhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell- derived PAI-1.
PtmThe signal sequence is not cleaved.
SimilarityBelongs to the serpin family. Ov-serpin subfamily. {ECO:0000305}.
Subcellular LocationCytoplasm. Secreted, extracellular space.
SubunitInteracts with PSMB1. {ECO:0000269|PubMed:14732874}.
  logo