MGP Database

MGP002205

Ontology/Pathway Information

Entrez Gene ID	5087
Gene Name	pre-B-cell leukemia homeobox 1
Gene Symbol	PBX1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IDA:UniProtKB	C	cytoplasm
GO:0005654	IDA:HPA	C	nucleoplasm
GO:0005634	IDA:UniProtKB	C	nucleus
GO:0005667	IEA:Ensembl	C	transcription factor complex
GO:0003677	IDA:UniProtKB	F	DNA binding
GO:0000978	IEA:Ensembl	F	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077	IEA:Ensembl	F	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700	NAS:ProtInc	F	sequence-specific DNA binding transcription factor activity
GO:0008134	IPI:UniProtKB	F	transcription factor binding
GO:0030325	IEA:Ensembl	P	adrenal gland development
GO:0009952	IEA:Ensembl	P	anterior/posterior pattern specification
GO:0001658	IEA:Ensembl	P	branching involved in ureteric bud morphogenesis
GO:0035162	IEA:Ensembl	P	embryonic hemopoiesis
GO:0030326	IEA:Ensembl	P	embryonic limb morphogenesis
GO:0048706	IEA:Ensembl	P	embryonic skeletal system development
GO:0045665	IEA:Ensembl	P	negative regulation of neuron differentiation
GO:0043433	IDA:UniProtKB	P	negative regulation of sequence-specific DNA binding transcription factor activity
GO:0008284	IEA:Ensembl	P	positive regulation of cell proliferation
GO:0010971	IEA:Ensembl	P	positive regulation of G2/M transition of mitotic cell cycle
GO:0009954	IEA:Ensembl	P	proximal/distal pattern formation
GO:0030278	IEA:Ensembl	P	regulation of ossification
GO:0007548	IEA:UniProtKB-KW	P	sex differentiation
GO:0048536	IEA:Ensembl	P	spleen development
GO:0006694	IEA:UniProtKB-KW	P	steroid biosynthetic process
GO:0048538	IEA:Ensembl	P	thymus development

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_111045	Developmental Biology
REACT_263856	Transcriptional regulation of pluripotent stem cells