MGP Database

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MGP002213

Ontology/Pathway Information

Entrez Gene ID5105
Gene Namephosphoenolpyruvate carboxykinase 1 (soluble)
Gene Symbol PCK1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 ISS:BHF-UCLCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0031406 IDA:BHF-UCLFcarboxylic acid binding
GO:0019003 IEA:EnsemblFGDP binding
GO:0005525 IDA:BHF-UCLFGTP binding
GO:0000287 IDA:BHF-UCLFmagnesium ion binding
GO:0030145 IDA:BHF-UCLFmanganese ion binding
GO:0004613 ISS:BHF-UCLFphosphoenolpyruvate carboxykinase (GTP) activity
GO:0005975 TAS:ReactomePcarbohydrate metabolic process
GO:0017144 TAS:ReactomePdrug metabolic process
GO:0006094 ISS:BHF-UCLPgluconeogenesis
GO:0042593 ISS:BHF-UCLPglucose homeostasis
GO:0006006 IMP:BHF-UCLPglucose metabolic process
GO:0046327 ISS:BHF-UCLPglycerol biosynthetic process from pyruvate
GO:0006475 IDA:UniProtKBPinternal protein amino acid acetylation
GO:0006107 IEA:EnsemblPoxaloacetate metabolic process
GO:0014823 IEA:EnsemblPresponse to activity
GO:0032868 IDA:BHF-UCLPresponse to insulin
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_121388Abacavir metabolism
REACT_121189Abacavir transport and metabolism
REACT_111045Developmental Biology
REACT_116125Disease
REACT_1520Gluconeogenesis
REACT_723Glucose metabolism
REACT_264090Glycogen storage diseases
REACT_111217Metabolism
REACT_474Metabolism of carbohydrates
REACT_264430Myoclonic epilepsy of Lafora
REACT_27161Transcriptional regulation of white adipocyte differentiation
SMP Pathway Links
SMP IDDescription
SMP00562Fructose-1,6-diphosphatase deficiency
SMP00128Gluconeogenesis
SMP00581Glycogenosis, Type IA. Von gierke disease
SMP00573Glycogenosis, Type IB
SMP00574Glycogenosis, Type IC
SMP00374Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease
SMP00196Leigh Syndrome
SMP00560Phosphoenolpyruvate carboxykinase deficiency 1 (PEPCK1)
SMP00558Primary hyperoxaluria II, PH2
SMP00334Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency)
SMP00212Pyruvate Dehydrogenase Complex Deficiency
SMP00559Pyruvate kinase deficiency
SMP00060Pyruvate Metabolism
SMP00563Triosephosphate isomerase
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