MGP Database

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MGP002230

Ontology/Pathway Information

Entrez Gene ID5163
Gene Namepyruvate dehydrogenase kinase, isozyme 1
Gene Symbol PDK1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005967 IEA:EnsemblCmitochondrial pyruvate dehydrogenase complex
GO:0005739 TAS:ProtIncCmitochondrion
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004672 IDA:UniProtKBFprotein kinase activity
GO:0004740 IDA:UniProtKBFpyruvate dehydrogenase (acetyl-transferring) kinase activity
GO:0008283 IMP:UniProtKBPcell proliferation
GO:0044237 TAS:ReactomePcellular metabolic process
GO:0006006 TAS:ProtIncPglucose metabolic process
GO:0097411 IMP:UniProtKBPhypoxia-inducible factor-1alpha signaling pathway
GO:0008631 IMP:UniProtKBPintrinsic apoptotic signaling pathway in response to oxidative stress
GO:0006468 IDA:GOCPprotein phosphorylation
GO:0006090 TAS:ReactomePpyruvate metabolic process
GO:0010510 TAS:ReactomePregulation of acetyl-CoA biosynthetic process from pyruvate
GO:0010906 IMP:UniProtKBPregulation of glucose metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_2071Pyruvate metabolism
REACT_1046Pyruvate metabolism and Citric Acid (TCA) cycle
REACT_12528Regulation of pyruvate dehydrogenase (PDH) complex
REACT_267785Signaling by Retinoic Acid
REACT_111102Signal Transduction
REACT_111083The citric acid (TCA) cycle and respiratory electron transport
SMP Pathway Links
SMP IDDescription
SMP00358Fc Epsilon Receptor I Signaling in Mast Cells
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