MGP Database

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MGP002239

Ontology/Pathway Information

Entrez Gene ID5187
Gene Nameperiod circadian clock 1
Gene Symbol PER1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005634 IEA:UniProtKB-SubCellCnucleus
GO:0031490 ISS:UniProtKBFchromatin DNA binding
GO:0070888 IDA:BHF-UCLFE-box binding
GO:0019900 IPI:UniProtKBFkinase binding
GO:0000978 IDA:BHF-UCLFRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004871 IEA:InterProFsignal transducer activity
GO:0000989 ISS:BHF-UCLFtranscription factor binding transcription factor activity
GO:0031625 IPI:UniProtKBFubiquitin protein ligase binding
GO:0032922 IDA:UniProtKBPcircadian regulation of gene expression
GO:0097167 ISS:UniProtKBPcircadian regulation of translation
GO:0007623 IEP:UniProtKBPcircadian rhythm
GO:0009649 TAS:ProtIncPentrainment of circadian clock
GO:0043153 ISS:UniProtKBPentrainment of circadian clock by photoperiod
GO:0043966 IDA:UniProtKBPhistone H3 acetylation
GO:0070932 ISS:UniProtKBPhistone H3 deacetylation
GO:0043967 IDA:UniProtKBPhistone H4 acetylation
GO:2000323 ISS:UniProtKBPnegative regulation of glucocorticoid receptor signaling pathway
GO:0043124 ISS:UniProtKBPnegative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046329 ISS:UniProtKBPnegative regulation of JNK cascade
GO:0045892 ISS:UniProtKBPnegative regulation of transcription, DNA-templated
GO:0000122 ISS:BHF-UCLPnegative regulation of transcription from RNA polymerase II promoter
GO:0045944 ISS:UniProtKBPpositive regulation of transcription from RNA polymerase II promoter
GO:0010608 ISS:UniProtKBPposttranscriptional regulation of gene expression
GO:0042752 ISS:UniProtKBPregulation of circadian rhythm
GO:1900015 ISS:UniProtKBPregulation of cytokine production involved in inflammatory response
GO:0042634 IMP:UniProtKBPregulation of hair cycle
GO:1900744 ISS:UniProtKBPregulation of p38MAPK cascade
GO:0002028 ISS:UniProtKBPregulation of sodium ion transport
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111118BMAL1:CLOCK,NPAS2 activates circadian gene expression
REACT_24941Circadian Clock
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