MGP Database

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MGP002255

Ontology/Pathway Information

Entrez Gene ID5211
Gene Namephosphofructokinase, liver
Gene Symbol PFKL
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005945 IDA:UniProtKBC6-phosphofructokinase complex
GO:0005829 IDA:UniProtKBCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016020 IDA:UniProtKBCmembrane
GO:0003872 IDA:UniProtKBF6-phosphofructokinase activity
GO:0005524 IDA:UniProtKBFATP binding
GO:0070095 IDA:BHF-UCLFfructose-6-phosphate binding
GO:0070061 IDA:BHF-UCLFfructose binding
GO:0042802 IPI:IntActFidentical protein binding
GO:0019900 IPI:BHF-UCLFkinase binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0005975 TAS:ReactomePcarbohydrate metabolic process
GO:0046835 IDA:GOCPcarbohydrate phosphorylation
GO:0030388 IDA:UniProtKBPfructose 1,6-bisphosphate metabolic process
GO:0006002 IDA:UniProtKBPfructose 6-phosphate metabolic process
GO:0006006 TAS:ReactomePglucose metabolic process
GO:0006096 IDA:UniProtKBPglycolytic process
GO:0046676 IEA:EnsemblPnegative regulation of insulin secretion
GO:0051289 IEA:EnsemblPprotein homotetramerization
GO:0051259 IDA:BHF-UCLPprotein oligomerization
GO:0009749 IDA:UniProtKBPresponse to glucose
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_116125Disease
REACT_723Glucose metabolism
REACT_264090Glycogen storage diseases
REACT_1383Glycolysis
REACT_111217Metabolism
REACT_474Metabolism of carbohydrates
REACT_264430Myoclonic epilepsy of Lafora
SMP Pathway Links
SMP IDDescription
SMP00064Fructose and Mannose Degradation
SMP00725Fructose intolerance, hereditary
SMP00561Fructosuria
SMP00518Glucose-6-phosphate dehydrogenase deficiency
SMP00031Pentose Phosphate Pathway
SMP00519Ribose-5-phosphate isomerase deficiency
SMP00520Transaldolase deficiency
SMP00654Warburg Effect
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