MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP002268

Ontology/Pathway Information

Entrez Gene ID5243
Gene NameATP-binding cassette, sub-family B (MDR/TAP), member 1
Gene Symbol ABCB1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:DFLATCcell surface
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016021 IBA:GO_CentralCintegral component of membrane
GO:0016020 TAS:ProtIncCmembrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0042626 IBA:GO_CentralFATPase activity, coupled to transmembrane movement of substances
GO:0005524 TAS:ProtIncFATP binding
GO:0005215 TAS:ProtIncFtransporter activity
GO:0008559 IEA:UniProtKB-ECFxenobiotic-transporting ATPase activity
GO:0006855 TAS:ReactomePdrug transmembrane transport
GO:0000086 IDA:DFLATPG2/M transition of mitotic cell cycle
GO:0042493 TAS:ProtIncPresponse to drug
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0072089 IMP:DFLATPstem cell proliferation
GO:0055085 IBA:GO_CentralPtransmembrane transport
GO:0006810 TAS:ProtIncPtransport
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_120801Abacavir transmembrane transport
REACT_121189Abacavir transport and metabolism
REACT_15480ABC-family proteins mediated transport
REACT_111217Metabolism
REACT_15518Transmembrane transport of small molecules
SMP Pathway Links
SMP IDDescription
SMP00640Acetaminophen Metabolism Pathway
SMP00260Clopidogrel Action Pathway
SMP00610Clopidogrel Metabolism Pathway
SMP00435Docetaxel Action Pathway
SMP00650Doxorubicin Metabolism Pathway
SMP00472Erlotinib Action Pathway
SMP00442Etoposide Action Pathway
SMP00601Etoposide Metabolism Pathway
SMP00433Irinotecan Action Pathway
SMP00600Irinotecan Metabolism Pathway
SMP00649Lamivudine Metabolism Pathway
SMP00652Mycophenolic Acid Metabolism Pathway
SMP00434Paclitaxel Action Pathway
SMP00636Venlafaxine Metabolism Pathway
SMP00436Vinblastine Action Pathway
SMP00437Vincristine Action Pathway
SMP00438Vindesine Action Pathway
SMP00439Vinorelbine Action Pathway
  logo