MGP Database

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MGP002278

Ontology/Pathway Information

Entrez Gene ID5265
Gene Nameserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
Gene Symbol SERPINA1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005783 IDA:UniProtKBCendoplasmic reticulum
GO:0005576 NAS:UniProtKBCextracellular region
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005794 IDA:UniProtKBCGolgi apparatus
GO:0031093 TAS:ReactomeCplatelet alpha granule lumen
GO:0005578 IEA:UniProtKB-SubCellCproteinaceous extracellular matrix
GO:0001948 IPI:UniProtKBFglycoprotein binding
GO:0042802 IPI:IntActFidentical protein binding
GO:0002020 IPI:UniProtKBFprotease binding
GO:0004867 NAS:UniProtKBFserine-type endopeptidase inhibitor activity
GO:0006953 IEA:UniProtKB-KWPacute-phase response
GO:0007596 TAS:ReactomePblood coagulation
GO:0010951 IBA:GO_CentralPnegative regulation of endopeptidase activity
GO:0030168 TAS:ReactomePplatelet activation
GO:0002576 TAS:ReactomePplatelet degranulation
GO:0030162 IBA:GO_CentralPregulation of proteolysis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_604Hemostasis
REACT_798Platelet activation, signaling and aggregation
REACT_318Platelet degranulation
REACT_1280Response to elevated platelet cytosolic Ca2+
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