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MGP002284

Record overview

MGPD IDMGP002284
Gene ID5281
SpeciesHomo sapiens (Human)
Gene Namephosphatidylinositol glycan anchor biosynthesis, class F
Gene Symbol PIGF
Alternate namesphosphatidylinositol-glycan biosynthesis class F protein; GPI11 homolog; PIG-F;
Chromosome2
Map Location2p21-p16
SummaryThis gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PIGF

Proteins

phosphatidylinositol-glycan biosynthesis class F protein isoform 1
Refseq ID:NP_002634
Protein GI:4505797
UniProt ID:Q07326
mRNA ID:NM_002643
Length:219
RefSeq Status:
MKDNDIKRLLYTHLLCIFSIILSVFIPSLFLENFSILETHLTWLCICSGFVTAVNLVLYLVVKPNTSSKRSSLSHKVTGFLKCCIYFLMSCFSFHVIFVL
YGAPLIELALETFLFAVILSTFTTVPCLCLLGPNLKAWLRVFSRNGVTSIWENSLQITTISSFVGAWLGALPIPLDWERPWQVWPISCTLGATFGYVAGL
VISPLWIYWNRKQLTYKNN
 
phosphatidylinositol-glycan biosynthesis class F protein isoform 2
Refseq ID:NP_775097
Protein GI:27894291
UniProt ID:Q07326
mRNA ID:NM_173074
Length:206
RefSeq Status:
MKDNDIKRLLYTHLLCIFSIILSVFIPSLFLENFSILETHLTWLCICSGFVTAVNLVLYLVVKPNTSSKRSSLSHKVTGFLKCCIYFLMSCFSFHVIFVL
YGAPLIELALETFLFAVILSTFTTVPCLCLLGPNLKAWLRVFSRNGVTSIWENSLQITTISSFVGAWLGALPIPLDWERPWQMTVERKRSTYRSLHVPCR
GLGTVK
 
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