MGP Database

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MGP002366

UniProt Annotations

Entry Information
Gene Namepolymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
Protein EntryRPAB4_HUMAN
UniProt IDP53803
SpeciesHuman
Comments
Comment typeDescription
FunctionDNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively.
SimilarityBelongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. {ECO:0000305}.
Subcellular LocationNucleus {ECO:0000250}.
SubunitComponent of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively. {ECO:0000250}.
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