MGP Database

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MGP002382

Ontology/Pathway Information

Entrez Gene ID5476
Gene Namecathepsin A
Gene Symbol CTSA
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005783 TAS:ProtIncCendoplasmic reticulum
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0043231 IDA:HPACintracellular membrane-bounded organelle
GO:0043202 TAS:ReactomeClysosomal lumen
GO:0005764 NAS:UniProtKBClysosome
GO:0016020 IDA:UniProtKBCmembrane
GO:0005654 IDA:HPACnucleoplasm
GO:0004180 TAS:ProtIncFcarboxypeptidase activity
GO:0008047 TAS:ProtIncFenzyme activator activity
GO:0004185 IEA:InterProFserine-type carboxypeptidase activity
GO:0006687 TAS:ReactomePglycosphingolipid metabolic process
GO:0006886 TAS:ProtIncPintracellular protein transport
GO:0043085 TAS:GOCPpositive regulation of catalytic activity
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006665 TAS:ReactomePsphingolipid metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_22426Asparagine N-linked glycosylation
REACT_22433Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
REACT_268132Defective ALG11 causes ALG11-CDG (CDG-1p)
REACT_267773Defective ALG12 causes ALG12-CDG (CDG-1g)
REACT_268645Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)
REACT_268144Defective ALG1 causes ALG1-CDG (CDG-1k)
REACT_268833Defective ALG2 causes ALG2-CDG (CDG-1i)
REACT_268185Defective ALG3 causes ALG3-CDG (CDG-1d)
REACT_267765Defective ALG6 causes ALG6-CDG (CDG-1c)
REACT_268459Defective ALG8 causes ALG8-CDG (CDG-1h)
REACT_268015Defective ALG9 causes ALG9-CDG (CDG-1l)
REACT_268438Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
REACT_268849Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2
REACT_268813Defective MAN1B1 causes MRT15
REACT_268600Defective MGAT2 causes MGAT2-CDG (CDG-2a)
REACT_267905Defective MOGS causes MOGS-CDG (CDG-2b)
REACT_268619Defective MPDU1 causes MPDU1-CDG (CDG-1f)
REACT_268458Defective RFT1 causes RFT1-CDG (CDG-1n)
REACT_116125Disease
REACT_267875Diseases associated with N-glycosylation of proteins
REACT_268324Diseases of glycosylation
REACT_116105Glycosphingolipid metabolism
REACT_6900Immune System
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_17015Metabolism of proteins
REACT_121399MHC class II antigen presentation
REACT_22161Post-translational protein modification
REACT_264366Sialic acid metabolism
REACT_19323Sphingolipid metabolism
REACT_22387Synthesis of substrates in N-glycan biosythesis
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