MGP Database

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MGP002387

Ontology/Pathway Information

Entrez Gene ID5498
Gene Nameprotoporphyrinogen oxidase
Gene Symbol PPOX
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0031305 IEA:EnsemblCintegral component of mitochondrial inner membrane
GO:0031304 ISS:UniProtKBCintrinsic component of mitochondrial inner membrane
GO:0005758 TAS:ReactomeCmitochondrial intermembrane space
GO:0031966 IMP:UniProtKBCmitochondrial membrane
GO:0050660 TAS:UniProtKBFflavin adenine dinucleotide binding
GO:0004729 IDA:UniProtKBFoxygen-dependent protoporphyrinogen oxidase activity
GO:0006783 IDA:UniProtKBPheme biosynthetic process
GO:0055114 IDA:UniProtKBPoxidation-reduction process
GO:0006779 IDA:UniProtKBPporphyrin-containing compound biosynthetic process
GO:0006778 TAS:ReactomePporphyrin-containing compound metabolic process
GO:0006782 IEA:UniProtKB-UniPathwayPprotoporphyrinogen IX biosynthetic process
GO:0042493 IEA:EnsemblPresponse to drug
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_9465Heme biosynthesis
REACT_111217Metabolism
REACT_9431Metabolism of porphyrins
SMP Pathway Links
SMP IDDescription
SMP00344Acute Intermittent Porphyria
SMP00345Congenital Erythropoietic Porphyria (CEP) or Gunther Disease
SMP00342Hereditary Coproporphyria (HCP)
SMP00346Porphyria Variegata (PV)
SMP00024Porphyrin Metabolism
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