MGP Database

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MGP002422

Ontology/Pathway Information

Entrez Gene ID5579
Gene Nameprotein kinase C, beta
Gene Symbol PRKCB
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005634 IDA:UniProtKBCnucleus
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0050681 IDA:UniProtKBFandrogen receptor binding
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0005246 IEA:EnsemblFcalcium channel regulator activity
GO:0003682 IDA:UniProtKBFchromatin binding
GO:0042393 IDA:UniProtKBFhistone binding
GO:0035403 IDA:UniProtKBFhistone kinase activity (H3-T6 specific)
GO:0030374 IMP:UniProtKBFligand-dependent nuclear receptor transcription coactivator activity
GO:0004697 TAS:ProtIncFprotein kinase C activity
GO:0005080 IPI:UniProtKBFprotein kinase C binding
GO:0004674 TAS:ReactomeFprotein serine/threonine kinase activity
GO:0008270 IEA:InterProFzinc ion binding
GO:0006915 IEA:UniProtKB-KWPapoptotic process
GO:0042113 ISS:UniProtKBPB cell activation
GO:0050853 ISS:UniProtKBPB cell receptor signaling pathway
GO:0007596 TAS:ReactomePblood coagulation
GO:0006816 IEA:EnsemblPcalcium ion transport
GO:0006874 IEA:EnsemblPcellular calcium ion homeostasis
GO:0071322 IEA:EnsemblPcellular response to carbohydrate stimulus
GO:0035408 IDA:UniProtKBPhistone H3-T6 phosphorylation
GO:0035556 IEA:InterProPintracellular signal transduction
GO:0042953 TAS:BHF-UCLPlipoprotein transport
GO:0010829 ISS:UniProtKBPnegative regulation of glucose transport
GO:0046627 ISS:UniProtKBPnegative regulation of insulin receptor signaling pathway
GO:0030168 TAS:ReactomePplatelet activation
GO:0045766 ISS:UniProtKBPpositive regulation of angiogenesis
GO:0050861 ISS:UniProtKBPpositive regulation of B cell receptor signaling pathway
GO:0043123 ISS:UniProtKBPpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092 ISS:UniProtKBPpositive regulation of NF-kappaB transcription factor activity
GO:0030949 ISS:UniProtKBPpositive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0006468 TAS:ProtIncPprotein phosphorylation
GO:0006357 IMP:UniProtKBPregulation of transcription from RNA polymerase II promoter
GO:0007165 NAS:ProtIncPsignal transduction
GO:0007268 TAS:ReactomePsynaptic transmission
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_118656Activation of NF-kappaB in B cells
REACT_75774Adaptive Immune System
REACT_264224beta-catenin independent WNT signaling
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_263908Depolymerisation of the Nuclear Lamina
REACT_1178Disinhibition of SNARE formation
REACT_118638Downstream signaling events of B Cell Receptor (BCR)
REACT_19333G alpha (z) signalling events
REACT_18347Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
REACT_19184GPCR downstream signaling
REACT_604Hemostasis
REACT_6900Immune System
REACT_765Mitotic Prophase
REACT_910M Phase
REACT_13685Neuronal System
REACT_15370Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
REACT_160255Nuclear Envelope Breakdown
REACT_264199PCP/CE pathway
REACT_798Platelet activation, signaling and aggregation
REACT_1280Response to elevated platelet cytosolic Ca2+
REACT_14797Signaling by GPCR
REACT_118773Signaling by the B Cell Receptor (BCR)
REACT_12529Signaling by VEGF
REACT_11045Signaling by Wnt
REACT_111102Signal Transduction
REACT_18307Trafficking of AMPA receptors
REACT_18422Trafficking of GluR2-containing AMPA receptors
REACT_13477Transmission across Chemical Synapses
REACT_264464VEGFA-VEGFR2 Pathway
REACT_264273VEGFR2 mediated cell proliferation
REACT_263890WNT5A-dependent internalization of FZD4
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