MGP Database

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MGP002429

Ontology/Pathway Information

Entrez Gene ID5588
Gene Nameprotein kinase C, theta
Gene Symbol PRKCQ
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0001772 IEA:EnsemblCimmunological synapse
GO:0005886 TAS:ReactomeCplasma membrane
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004697 IEA:UniProtKB-ECFprotein kinase C activity
GO:0004674 NAS:UniProtKBFprotein serine/threonine kinase activity
GO:0004842 TAS:ReactomeFubiquitin-protein transferase activity
GO:0006915 TAS:ReactomePapoptotic process
GO:0007411 TAS:ReactomePaxon guidance
GO:0007596 TAS:ReactomePblood coagulation
GO:0006921 TAS:ReactomePcellular component disassembly involved in execution phase of apoptosis
GO:0038095 TAS:ReactomePFc-epsilon receptor signaling pathway
GO:0006954 IEA:UniProtKB-KWPinflammatory response
GO:0045087 TAS:ReactomePinnate immune response
GO:0035556 NAS:UniProtKBPintracellular signal transduction
GO:0006509 ISS:BHF-UCLPmembrane protein ectodomain proteolysis
GO:0046627 IMP:UniProtKBPnegative regulation of insulin receptor signaling pathway
GO:0070233 IMP:UniProtKBPnegative regulation of T cell apoptotic process
GO:0007603 TAS:ReactomePphototransduction, visible light
GO:0030168 TAS:ReactomePplatelet activation
GO:0032740 ISS:UniProtKBPpositive regulation of interleukin-17 production
GO:0045086 IEA:EnsemblPpositive regulation of interleukin-2 biosynthetic process
GO:0032753 ISS:UniProtKBPpositive regulation of interleukin-4 production
GO:0051092 IDA:UniProtKBPpositive regulation of NF-kappaB transcription factor activity
GO:0050870 ISS:UniProtKBPpositive regulation of T cell activation
GO:0042102 IEA:EnsemblPpositive regulation of T cell proliferation
GO:2000318 ISS:UniProtKBPpositive regulation of T-helper 17 type immune response
GO:2000570 ISS:UniProtKBPpositive regulation of T-helper 2 cell activation
GO:0016567 TAS:GOCPprotein ubiquitination
GO:0001558 NAS:UniProtKBPregulation of cell growth
GO:0090330 ISS:UniProtKBPregulation of platelet aggregation
GO:0022400 TAS:ReactomePregulation of rhodopsin mediated signaling pathway
GO:0006355 ISS:UniProtKBPregulation of transcription, DNA-templated
GO:0016056 TAS:ReactomePrhodopsin mediated signaling pathway
GO:0050852 TAS:ReactomePT cell receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_578Apoptosis
REACT_107Apoptotic cleavage of cellular proteins
REACT_995Apoptotic execution phase
REACT_18266Axon guidance
REACT_111045Developmental Biology
REACT_116125Disease
REACT_160102Diseases associated with visual transduction
REACT_12555Downstream TCR signaling
REACT_2202Effects of PIP2 hydrolysis
REACT_163936Fc epsilon receptor (FCERI) signaling
REACT_163994FCERI mediated NF-kB activation
REACT_18283G alpha (q) signalling events
REACT_19333G alpha (z) signalling events
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184GPCR downstream signaling
REACT_604Hemostasis
REACT_6900Immune System
REACT_163919Inactivation, recovery and regulation of the phototransduction cascade
REACT_6802Innate Immune System
REACT_22237Netrin-1 signaling
REACT_798Platelet activation, signaling and aggregation
REACT_268456Programmed Cell Death
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
REACT_12526TCR signaling
REACT_163722The phototransduction cascade
REACT_160125Visual phototransduction
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