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MGP002442

Record overview

MGPD IDMGP002442
Gene ID5603
SpeciesHomo sapiens (Human)
Gene Namemitogen-activated protein kinase 13
Gene Symbol MAPK13
SynonymsSAPK4; PRKM13; MAPK 13; MAPK-13; p38delta;
Alternate namesmitogen-activated protein kinase 13; MAP kinase 13; MAP kinase p38 delta; mitogen-activated protein kinase p38 delta; stress-activated protein kinase 4;
Chromosome6
Map Location6p21.31
EC Number2.7.11.24
SummaryThis gene encodes a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The encoded protein is a p38 MAP kinase and is activated by proinflammatory cytokines and cellular stress. Substrates of the encoded protein include the transcription factor ATF2 and the microtubule dynamics regulator stathmin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
OrthologsView orthologs and multiple alignments for MAPK13

Proteins

mitogen-activated protein kinase 13
Refseq ID:NP_002745
Protein GI:4506085
UniProt ID:O15264
mRNA ID:NM_002754
Length:365
RefSeq Status:
MSLIRKKGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNF
YDFYLVMPFMQTDLQKIMGMEFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMTGYVVTRWYRAPEVILSWMHY
NQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAA
QALTHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQHIYKEIVNFSPIARKDSRRRSGMKL
 
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