MGP Database

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MGP002456

Ontology/Pathway Information

Entrez Gene ID5625
Gene Nameproline dehydrogenase (oxidase) 1
Gene Symbol PRODH
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005743 TAS:ReactomeCmitochondrial inner membrane
GO:0005759 IEA:UniProtKB-SubCellCmitochondrial matrix
GO:0071949 IDA:UniProtKBFFAD binding
GO:0004657 IDA:UniProtKBFproline dehydrogenase activity
GO:0019470 TAS:BHF-UCLP4-hydroxyproline catabolic process
GO:0034641 TAS:ReactomePcellular nitrogen compound metabolic process
GO:0008631 NAS:UniProtKBPintrinsic apoptotic signaling pathway in response to oxidative stress
GO:0006562 TAS:ReactomePproline catabolic process
GO:0010133 IEA:UniProtKB-UniPathwayPproline catabolic process to glutamate
GO:0006560 TAS:ProtIncPproline metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_13Metabolism of amino acids and derivatives
REACT_1002Proline catabolism
SMP Pathway Links
SMP IDDescription
SMP00020Arginine and Proline Metabolism
SMP00362Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency)
SMP00504Creatine deficiency, guanidinoacetate methyltransferase deficiency
SMP00188Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency)
SMP00506Hyperornithinemia-hyperammonemia-homocitrullinuria [HHH-syndrome]
SMP00505Hyperornithinemia with gyrate atrophy (HOGA)
SMP00361Hyperprolinemia Type I
SMP00360Hyperprolinemia Type II
SMP00507L-arginine:glycine amidinotransferase deficiency
SMP00363Ornithine Aminotransferase Deficiency (OAT Deficiency)
SMP00207Prolidase Deficiency (PD)
SMP00208Prolinemia Type II
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