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MGP002459

Record overview

MGPD IDMGP002459
Gene ID5634
SpeciesHomo sapiens (Human)
Gene Namephosphoribosyl pyrophosphate synthetase 2
Gene Symbol PRPS2
SynonymsPRSII;
Alternate namesribose-phosphate pyrophosphokinase 2; PPRibP synthetase; PRS-II; phosphoribosyl pyrophosphate synthase II; ribose-phosphate diphosphokinase 2;
ChromosomeX
Map LocationXp22.2
EC Number2.7.6.1
SummaryThis gene encodes a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
OrthologsView orthologs and multiple alignments for PRPS2

Proteins

ribose-phosphate pyrophosphokinase 2 isoform 1
Refseq ID:NP_001034180
Protein GI:84875539
UniProt ID:P11908
mRNA ID:NM_001039091
Length:321
RefSeq Status:
MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKK
DKVGESRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERK
KANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILA
EAIRRTHNGESVSYLFSHVPL
 
ribose-phosphate pyrophosphokinase 2 isoform 2
Refseq ID:NP_002756
Protein GI:4506129
UniProt ID:P11908
mRNA ID:NM_002765
Length:318
RefSeq Status:
MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKK
DKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKAN
EVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAI
RRTHNGESVSYLFSHVPL
 
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