MGP Database

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MGP002503

UniProt Annotations

Entry Information
Gene Nameproteasome (prosome, macropain) 26S subunit, non-ATPase, 12
Protein EntryPSD12_HUMAN
UniProt IDO00232
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=O00232-1; Sequence=Displayed; Name=2; IsoId=O00232-2; Sequence=VSP_042718; Note=No experimental confirmation available.;
FunctionActs as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Sequence CautionSequence=AAH65826.1; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the proteasome subunit p55 family. {ECO:0000305}.
SimilarityContains 1 PCI domain. {ECO:0000305}.
SubunitComponent of the PA700 complex.
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