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MGP002512

Record overview

MGPD IDMGP002512
Gene ID5729
SpeciesHomo sapiens (Human)
Gene Nameprostaglandin D2 receptor (DP)
Gene Symbol PTGDR
SynonymsDP; AS1; DP1; ASRT1; PTGDR1;
Alternate namesprostaglandin D2 receptor; PGD2 receptor;
Chromosome14
Map Location14q22.1
SummaryThis gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein is reported to be a receptor for prostaglandin D2, which is a mediator of allergic inflammation and allergic airway inflammation in asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
OrthologsView orthologs and multiple alignments for PTGDR

Proteins

prostaglandin D2 receptor isoform 1
Refseq ID:NP_000944
Protein GI:28466969
UniProt ID:Q13258
mRNA ID:NM_000953
Length:359
RefSeq Status:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPAL
DNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYS
VLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTS
EEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
 
prostaglandin D2 receptor isoform 2
Refseq ID:NP_001268398
Protein GI:527317384
UniProt ID:Q13258
mRNA ID:NM_001281469
Length:296
RefSeq Status:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPAL
DNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYS
VLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIAFVPGVPAKTPGSR
 
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