MGP Database

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MGP002515

UniProt Annotations

Entry Information
Gene Nameprostaglandin E receptor 2 (subtype EP2), 53kDa
Protein EntryPE2R2_HUMAN
UniProt IDP43116
SpeciesHuman
Comments
Comment typeDescription
FunctionReceptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
SimilarityBelongs to the G-protein coupled receptor 1 family. {ECO:0000255|PROSITE-ProRule:PRU00521}.
Subcellular LocationCell membrane; Multi-pass membrane protein.
Tissue SpecificityPlacenta and lung.
Web ResourceName=SeattleSNPs; URL="http://pga.gs.washington.edu/data/ptger2/";
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