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MGP002516

Record overview

MGPD IDMGP002516
Gene ID5733
SpeciesHomo sapiens (Human)
Gene Nameprostaglandin E receptor 3 (subtype EP3)
Gene Symbol PTGER3
SynonymsEP3; EP3e; EP3-I; EP3-II; EP3-IV; PGE2-R; EP3-III;
Alternate namesprostaglandin E2 receptor EP3 subtype; PGE receptor, EP3 subtype; PGE2 receptor EP3 subtype; prostaglandin E receotor EP3 subtype 3 isoform; prostaglandin receptor (PGE-2); prostanoid EP3 receptor;
Chromosome1
Map Location1p31.2
SummaryThe protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
OrthologsView orthologs and multiple alignments for PTGER3

Proteins

prostaglandin E2 receptor EP3 subtype isoform 4
Refseq ID:NP_001119516
Protein GI:186659506
UniProt ID:P43115
mRNA ID:NM_001126044
Length:390
RefSeq Status:
MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDL
VGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYT
VQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRYHTNNYASSSTSLPCQCSSTLMWSDHLER
 
prostaglandin E2 receptor EP3 subtype isoform 4
Refseq ID:NP_942007
Protein GI:38505178
UniProt ID:P43115
mRNA ID:NM_198714
Length:390
RefSeq Status:
Protein sequence is identical to GI:186659506 (mRNA isoform)
 
prostaglandin E2 receptor EP3 subtype isoform 4
Refseq ID:NP_942012
Protein GI:38505188
UniProt ID:P43115
mRNA ID:NM_198719
Length:390
RefSeq Status:
Protein sequence is identical to GI:186659506 (mRNA isoform)
 
prostaglandin E2 receptor EP3 subtype isoform 5
Refseq ID:NP_942008
Protein GI:38505180
UniProt ID:P43115
mRNA ID:NM_198715
Length:388
RefSeq Status:
MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDL
VGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYT
VQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQVANAVSSCSNDGQKGQPISLSNEIIQTEA
 
prostaglandin E2 receptor EP3 subtype isoform 6
Refseq ID:NP_942009
Protein GI:38505182
UniProt ID:P43115
mRNA ID:NM_198716
Length:374
RefSeq Status:
MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDL
VGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYT
VQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQMRKRRLREQEEFWGN
 
prostaglandin E2 receptor EP3 subtype isoform 7
Refseq ID:NP_942010
Protein GI:38505184
UniProt ID:P43115
mRNA ID:NM_198717
Length:365
RefSeq Status:
MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDL
VGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYT
VQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQEEFWGN
 
prostaglandin E2 receptor EP3 subtype isoform 8
Refseq ID:NP_942011
Protein GI:38505186
UniProt ID:O00325
mRNA ID:NM_198718
Length:418
RefSeq Status:
MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDL
VGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYT
VQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQMRKRRLREQLICSLQNSQIQRATAHCGQVQTYRVLNREEME
VLVSSINVYTRISTVKTE
 
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