MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP002532

Ontology/Pathway Information

Entrez Gene ID5788
Gene Nameprotein tyrosine phosphatase, receptor type, C
Gene Symbol PTPRC
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009897 IDA:MGICexternal side of plasma membrane
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005925 ISS:UniProtKBCfocal adhesion
GO:0005887 ISS:UniProtKBCintegral component of plasma membrane
GO:0016020 IDA:UniProtKBCmembrane
GO:0045121 IEA:UniProtKB-SubCellCmembrane raft
GO:0005886 TAS:ReactomeCplasma membrane
GO:0019901 IPI:UniProtKBFprotein kinase binding
GO:0004725 IDA:UniProtKBFprotein tyrosine phosphatase activity
GO:0005001 TAS:ProtIncFtransmembrane receptor protein tyrosine phosphatase activity
GO:0007411 TAS:ReactomePaxon guidance
GO:0042100 ISS:UniProtKBPB cell proliferation
GO:0050853 ISS:UniProtKBPB cell receptor signaling pathway
GO:0048539 IMP:UniProtKBPbone marrow development
GO:0044770 IMP:UniProtKBPcell cycle phase transition
GO:0007166 TAS:ProtIncPcell surface receptor signaling pathway
GO:0051607 ISS:UniProtKBPdefense response to virus
GO:0016311 ISS:UniProtKBPdephosphorylation
GO:0002244 IMP:UniProtKBPhematopoietic progenitor cell differentiation
GO:0002378 IMP:UniProtKBPimmunoglobulin biosynthetic process
GO:0006933 IMP:UniProtKBPnegative regulation of cell adhesion involved in substrate-bound cell migration
GO:0001960 ISS:UniProtKBPnegative regulation of cytokine-mediated signaling pathway
GO:0006469 IDA:UniProtKBPnegative regulation of protein kinase activity
GO:0001915 ISS:UniProtKBPnegative regulation of T cell mediated cytotoxicity
GO:0035335 IDA:GOCPpeptidyl-tyrosine dephosphorylation
GO:0050857 ISS:UniProtKBPpositive regulation of antigen receptor-mediated signaling pathway
GO:0030890 IMP:UniProtKBPpositive regulation of B cell proliferation
GO:2000473 IMP:UniProtKBPpositive regulation of hematopoietic stem cell migration
GO:0045860 NAS:UniProtKBPpositive regulation of protein kinase activity
GO:2000648 IMP:UniProtKBPpositive regulation of stem cell proliferation
GO:0042102 ISS:UniProtKBPpositive regulation of T cell proliferation
GO:0006470 ISS:UniProtKBPprotein dephosphorylation
GO:0051726 ISS:UniProtKBPregulation of cell cycle
GO:0051209 ISS:UniProtKBPrelease of sequestered calcium ion into cytosol
GO:0048864 IMP:UniProtKBPstem cell development
GO:0030217 ISS:UniProtKBPT cell differentiation
GO:0050852 IDA:UniProtKBPT cell receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_18266Axon guidance
REACT_111045Developmental Biology
REACT_6900Immune System
REACT_19200Other semaphorin interactions
REACT_12582Phosphorylation of CD3 and TCR zeta chains
REACT_19271Semaphorin interactions
REACT_12526TCR signaling
  logo