MGP Database

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MGP002544

UniProt Annotations

Entry Information
Gene Namephosphate cytidylyltransferase 2, ethanolamine
Protein Entry
UniProt ID
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=4; Name=1; IsoId=Q99447-1; Sequence=Displayed; Name=2; IsoId=Q99447-2; Sequence=VSP_045131; Name=3; IsoId=Q99447-3; Sequence=VSP_046844; Note=No experimental confirmation available. Gene prediction based on cDNA data.; Name=4; IsoId=Q99447-4; Sequence=VSP_054615; Note=No experimental confirmation available.;
Catalytic ActivityCTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine.
FunctionPlays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP-ethanolamine.
PathwayPhospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 2/3.
SimilarityBelongs to the cytidylyltransferase family. {ECO:0000305}.
Tissue SpecificityStrongest expression in liver, heart, and skeletal muscle.
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