MGP Database

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MGP002549

Ontology/Pathway Information

Entrez Gene ID5860
Gene Namequinoid dihydropteridine reductase
Gene Symbol QDPR
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:LIFEdbCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005739 IEA:EnsemblCmitochondrion
GO:0043005 IEA:EnsemblCneuron projection
GO:0004155 EXP:ReactomeF6,7-dihydropteridine reductase activity
GO:0009055 TAS:UniProtKBFelectron carrier activity
GO:0070404 IEA:EnsemblFNADH binding
GO:0070402 IEA:EnsemblFNADPH binding
GO:0006520 TAS:ProtIncPcellular amino acid metabolic process
GO:0034641 TAS:ReactomePcellular nitrogen compound metabolic process
GO:0035690 IEA:EnsemblPcellular response to drug
GO:0051066 TAS:ProtIncPdihydrobiopterin metabolic process
GO:0001889 IEA:EnsemblPliver development
GO:0006559 TAS:ReactomePL-phenylalanine catabolic process
GO:0010044 IEA:EnsemblPresponse to aluminum ion
GO:0033762 IEA:EnsemblPresponse to glucagon
GO:0010288 IEA:EnsemblPresponse to lead ion
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006729 IEA:UniProtKB-KWPtetrahydrobiopterin biosynthetic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_13Metabolism of amino acids and derivatives
REACT_1786Phenylalanine and tyrosine catabolism
SMP Pathway Links
SMP IDDescription
SMP00486Dopa-responsive dystonia
SMP00487Hyperphenylalaniemia due to guanosine triphosphate cyclohydrolase deficiency
SMP00488Hyperphenylalaninemia due to 6-pyruvoyltetrahydropterin synthase deficiency (ptps)
SMP00489Hyperphenylalaninemia due to dhpr-deficiency
SMP00005Pterine Biosynthesis
SMP00490Segawa syndrome
SMP00491Sepiapterin reductase deficiency
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