MGP Database

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MGP002576

UniProt Annotations

Entry Information
Gene NameRAN binding protein 1
Protein Entry
UniProt ID
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=P43487-1; Sequence=Displayed; Name=2; IsoId=P43487-2; Sequence=VSP_055104;
FunctionInhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane.
InteractionP29372:MPG; NbExp=1; IntAct=EBI-1032909, EBI-1043398;
SimilarityBelongs to the RANBP1 family. {ECO:0000305}.
SimilarityContains 1 RanBD1 domain. {ECO:0000255|PROSITE- ProRule:PRU00164}.
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