MGP Database

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MGP002586

Ontology/Pathway Information

Entrez Gene ID5921
Gene NameRAS p21 protein activator (GTPase activating protein) 1
Gene Symbol RASA1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 NAS:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0031235 IBA:GO_CentralCintrinsic component of the cytoplasmic side of the plasma membrane
GO:0001726 IEA:EnsemblCruffle
GO:0001948 IPI:UniProtKBFglycoprotein binding
GO:0051020 IPI:UniProtKBFGTPase binding
GO:0019870 NAS:UniProtKBFpotassium channel inhibitor activity
GO:0005099 IBA:GO_CentralFRas GTPase activator activity
GO:0005102 IPI:UniProtKBFreceptor binding
GO:0048514 IMP:UniProtKBPblood vessel morphogenesis
GO:0009790 ISS:UniProtKBPembryo development
GO:0035556 NAS:UniProtKBPintracellular signal transduction
GO:0000281 ISS:UniProtKBPmitotic cytokinesis
GO:0007162 IDA:UniProtKBPnegative regulation of cell adhesion
GO:0001953 IDA:UniProtKBPnegative regulation of cell-matrix adhesion
GO:0043524 ISS:UniProtKBPnegative regulation of neuron apoptotic process
GO:0046580 IBA:GO_CentralPnegative regulation of Ras protein signal transduction
GO:0032320 IBA:GO_CentralPpositive regulation of Ras GTPase activity
GO:0030833 IDA:UniProtKBPregulation of actin filament polymerization
GO:0008360 NAS:UniProtKBPregulation of cell shape
GO:0051252 NAS:UniProtKBPregulation of RNA metabolic process
GO:0007165 IDA:UniProtKBPsignal transduction
GO:0001570 ISS:UniProtKBPvasculogenesis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18266Axon guidance
REACT_111045Developmental Biology
REACT_17025Downstream signal transduction
REACT_263952EPHB-mediated forward signaling
REACT_264068EPH-Ephrin signaling
REACT_16888Signaling by PDGF
REACT_12529Signaling by VEGF
REACT_111102Signal Transduction
REACT_264464VEGFA-VEGFR2 Pathway
REACT_264273VEGFR2 mediated cell proliferation
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