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MGP002608

Record overview

MGPD IDMGP002608
Gene ID5973
SpeciesHomo sapiens (Human)
Gene Namerenin binding protein
Gene Symbol RENBP
SynonymsRBP; RNBP;
Alternate namesN-acylglucosamine 2-epimerase; AGE; GlcNAc 2-epimerase; N-acetyl-D-glucosamine 2-epimerase;
ChromosomeX
Map LocationXq28
EC Number5.1.3.8
SummaryThe gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for RENBP

Proteins

N-acylglucosamine 2-epimerase
Refseq ID:NP_002901
Protein GI:213417820
UniProt ID:P51606
mRNA ID:NM_002910
Length:427
RefSeq Status:
MSKGLPARQDMEKERETLQAWKERVGQELDRVVAFWMEHSHDQEHGGFFTCLGREGRVYDDLKYVWLQGRQVWMYCRLYRTFERFRHAQLLDAAKAGGEF
LLRYARVAPPGKKCAFVLTRDGRPVKVQRTIFSECFYTMAMNELWRATGEVRYQTEAVEMMDQIVHWVQEDASGLGRPQLQGAPAAEPMAVPMMLLNLVE
QLGEADEELAGKYAELGDWCARRILQHVQRDGQAVLENVSEGGKELPGCLGRQQNPGHTLEAGWFLLRHCIRKGDPELRAHVIDKFLLLPFHSGWDPDHG
GLFYFQDADNFCPTQLEWAMKLWWPHSEAMIAFLMGYSDSGDPVLLRLFYQVAEYTFRQFRDPEYGEWFGYLSREGKVALSIKGGPFKGCFHVPRCLAMC
EEMLGALLSRPAPAPSPAPTPACRGAE
 
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