MGP Database

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MGP002645

Ontology/Pathway Information

Entrez Gene ID6119
Gene Namereplication protein A3, 14kDa
Gene Symbol RPA3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005662 IDA:UniProtKBCDNA replication factor A complex
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0003684 IDA:UniProtKBFdamaged DNA binding
GO:0003697 IDA:UniProtKBFsingle-stranded DNA binding
GO:0006284 IDA:UniProtKBPbase-excision repair
GO:0000730 TAS:ReactomePDNA recombinase assembly
GO:0006281 TAS:ReactomePDNA repair
GO:0006260 IMP:UniProtKBPDNA replication
GO:0006271 TAS:ReactomePDNA strand elongation involved in DNA replication
GO:0006302 TAS:ReactomePdouble-strand break repair
GO:0000724 IMP:UniProtKBPdouble-strand break repair via homologous recombination
GO:0000082 TAS:ReactomePG1/S transition of mitotic cell cycle
GO:0006298 IMP:UniProtKBPmismatch repair
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0006289 IMP:UniProtKBPnucleotide-excision repair
GO:0000718 TAS:ReactomePnucleotide-excision repair, DNA damage removal
GO:0006297 TAS:ReactomePnucleotide-excision repair, DNA gap filling
GO:0042127 IEA:EnsemblPregulation of cell proliferation
GO:0007346 IEA:EnsemblPregulation of mitotic cell cycle
GO:0000723 TAS:ReactomePtelomere maintenance
GO:0000722 TAS:ReactomePtelomere maintenance via recombination
GO:0032201 TAS:ReactomePtelomere maintenance via semi-conservative replication
GO:0006283 TAS:ReactomePtranscription-coupled nucleotide-excision repair
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6769Activation of ATR in response to replication stress
REACT_1095Activation of the pre-replicative complex
REACT_2141Assembly of the RAD51-ssDNA nucleoprotein complex
REACT_115566Cell Cycle
REACT_1538Cell Cycle Checkpoints
REACT_152Cell Cycle, Mitotic
REACT_120956Cellular responses to stress
REACT_263897Cellular response to heat stress
REACT_22172Chromosome Maintenance
REACT_216DNA Repair
REACT_383DNA Replication
REACT_734DNA Replication Pre-Initiation
REACT_932DNA strand elongation
REACT_2054Double-Strand Break Repair
REACT_311Dual incision reaction in GG-NER
REACT_8030Extension of Telomeres
REACT_257Formation of incision complex in GG-NER
REACT_1783G1/S Transition
REACT_828G2/M Checkpoints
REACT_1998Gap-filling DNA repair synthesis and ligation in GG-NER
REACT_74Gap-filling DNA repair synthesis and ligation in TC-NER
REACT_2253Global Genomic NER (GG-NER)
REACT_1763Homologous DNA pairing and strand exchange
REACT_1874Homologous Recombination Repair
REACT_1587Homologous recombination repair of replication-independent double-strand breaks
REACT_264071HSF1 activation
REACT_312Lagging Strand Synthesis
REACT_111183Meiosis
REACT_27271Meiotic recombination
REACT_1725M/G1 Transition
REACT_264442Mismatch Repair
REACT_264347Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
REACT_264501Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
REACT_21267Mitotic G1-G1/S phases
REACT_1826Nucleotide Excision Repair
REACT_408Presynaptic phase of homologous DNA pairing and strand exchange
REACT_2055Processing of DNA double-strand break ends
REACT_8027Processive synthesis on the C-strand of the telomere
REACT_1385Processive synthesis on the lagging strand
REACT_264487Regulation of HSF1-mediated heat shock response
REACT_70Removal of the Flap Intermediate
REACT_7999Removal of the Flap Intermediate from the C-strand
REACT_1993Repair synthesis for gap-filling by DNA polymerase in TC-NER
REACT_378Repair synthesis of patch ~27-30 bases long by DNA polymerase
REACT_899S Phase
REACT_2014Synthesis of DNA
REACT_7961Telomere C-strand (Lagging Strand) Synthesis
REACT_7970Telomere Maintenance
REACT_1628Transcription-coupled NER (TC-NER)
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