MGP Database

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MGP002703

Ontology/Pathway Information

Entrez Gene ID6198
Gene Nameribosomal protein S6 kinase, 70kDa, polypeptide 1
Gene Symbol RPS6KB1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030054 IEA:UniProtKB-KWCcell junction
GO:0009986 IEA:EnsemblCcell surface
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005741 IEA:UniProtKB-SubCellCmitochondrial outer membrane
GO:0005739 IDA:UniProtKBCmitochondrion
GO:0043005 IEA:UniProtKB-SubCellCneuron projection
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0048471 IEA:EnsemblCperinuclear region of cytoplasm
GO:0045202 IEA:UniProtKB-KWCsynapse
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0042277 IEA:EnsemblFpeptide binding
GO:0004672 IDA:UniProtKBFprotein kinase activity
GO:0004712 IDA:MGIFprotein serine/threonine/tyrosine kinase activity
GO:0004711 IEA:EnsemblFribosomal protein S6 kinase activity
GO:0007568 IEA:EnsemblPaging
GO:0006915 IEA:UniProtKB-KWPapoptotic process
GO:0016477 IEA:EnsemblPcell migration
GO:0071363 IDA:UniProtKBPcellular response to growth factor stimulus
GO:0000082 IMP:UniProtKBPG1/S transition of mitotic cell cycle
GO:0007281 IEA:EnsemblPgerm cell development
GO:0008286 TAS:ReactomePinsulin receptor signaling pathway
GO:0007616 IEA:EnsemblPlong-term memory
GO:0043066 IMP:UniProtKBPnegative regulation of apoptotic process
GO:2001237 IEA:EnsemblPnegative regulation of extrinsic apoptotic signaling pathway
GO:0046627 IMP:UniProtKBPnegative regulation of insulin receptor signaling pathway
GO:0048015 TAS:UniProtKBPphosphatidylinositol-mediated signaling
GO:0045931 IMP:UniProtKBPpositive regulation of mitotic cell cycle
GO:0048633 IEA:EnsemblPpositive regulation of skeletal muscle tissue growth
GO:0014911 IEA:EnsemblPpositive regulation of smooth muscle cell migration
GO:0048661 IEA:EnsemblPpositive regulation of smooth muscle cell proliferation
GO:0045727 IMP:UniProtKBPpositive regulation of translation
GO:0045948 IMP:UniProtKBPpositive regulation of translational initiation
GO:0043491 IEA:EnsemblPprotein kinase B signaling
GO:0006468 IDA:GOCPprotein phosphorylation
GO:0046324 IEA:EnsemblPregulation of glucose import
GO:0042493 IEA:EnsemblPresponse to drug
GO:0014878 IEA:EnsemblPresponse to electrical stimulus involved in regulation of muscle adaptation
GO:0045471 IEA:EnsemblPresponse to ethanol
GO:0033762 IEA:EnsemblPresponse to glucagon
GO:0051384 IEA:EnsemblPresponse to glucocorticoid
GO:0009749 IEA:EnsemblPresponse to glucose
GO:0009408 IEA:EnsemblPresponse to heat
GO:0043201 IEA:EnsemblPresponse to leucine
GO:0032496 IEA:EnsemblPresponse to lipopolysaccharide
GO:0009612 IEA:EnsemblPresponse to mechanical stimulus
GO:0007584 IEA:EnsemblPresponse to nutrient
GO:0033574 IEA:EnsemblPresponse to testosterone
GO:0009636 IEA:EnsemblPresponse to toxic substance
GO:0034612 IEA:EnsemblPresponse to tumor necrosis factor
GO:0009611 IEA:EnsemblPresponse to wounding
GO:0007165 TAS:ProtIncPsignal transduction
GO:0014732 IEA:EnsemblPskeletal muscle atrophy
GO:0003009 IEA:EnsemblPskeletal muscle contraction
GO:0031929 IDA:UniProtKBPTOR signaling
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_150210IGF1R signaling cascade
REACT_1195Insulin receptor signalling cascade
REACT_332IRS-mediated signalling
REACT_762IRS-related events
REACT_150203IRS-related events triggered by IGF1R
REACT_6964mTORC1-mediated signalling
REACT_6838mTOR signalling
REACT_976PI3K Cascade
REACT_456PKB-mediated events
REACT_6754S6K1-mediated signalling
REACT_6772S6K1 signalling
REACT_498Signaling by Insulin receptor
REACT_150359Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
REACT_111102Signal Transduction
SMP Pathway Links
SMP IDDescription
SMP00682Leucine Stimulation on Insulin Signaling
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