MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP002751

Record overview

MGPD IDMGP002751
Gene ID6307
SpeciesHomo sapiens (Human)
Gene Namemethylsterol monooxygenase 1
Gene Symbol MSMO1
SynonymsDESP4; ERG25; SC4MOL;
Alternate namesmethylsterol monooxygenase 1; C-4 methyl sterol; C-4 methylsterol oxidase;
Chromosome4
Map Location4q32-q34
EC Number1.14.13.72
SummarySterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein. It contains a set of putative metal binding motifs with similarity to that seen in a family of membrane desaturases-hydroxylases. The protein is localized to the endoplasmic reticulum membrane and is believed to function in cholesterol biosynthesis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for MSMO1

Proteins

methylsterol monooxygenase 1 isoform 1
Refseq ID:NP_006736
Protein GI:5803157
UniProt ID:Q15800
mRNA ID:NM_006745
Length:293
RefSeq Status:
MATNESVSIFSSASLAVEYVDSLLPENPLQEPFKNAWNYMLNNYTKFQIATWGSLIVHEALYFLFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCFKV
LLFNHFCIQLPLICGTYYFTEYFNIPYDWERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLETLILGTGFF
IGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE
 
methylsterol monooxygenase 1 isoform 2
Refseq ID:NP_001017369
Protein GI:62865628
UniProt ID:Q15800
mRNA ID:NM_001017369
Length:162
RefSeq Status:
MPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGY
DIPLNPLNLIPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE
 
  logo