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MGP002789

Record overview

MGPD IDMGP002789
Gene ID6374
SpeciesHomo sapiens (Human)
Gene Namechemokine (C-X-C motif) ligand 5
Gene Symbol CXCL5
SynonymsSCYB5; ENA-78;
Alternate namesC-X-C motif chemokine 5; epithelial-derived neutrophil-activating protein 78; neutrophil-activating peptide ENA-78; neutrophil-activating protein 78; small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78);
Chromosome4
Map Location4q13.3
SummaryThis gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. [provided by RefSeq, May 2013]
OrthologsView orthologs and multiple alignments for CXCL5

Proteins

C-X-C motif chemokine 5 precursor
Refseq ID:NP_002985
Protein GI:4506849
UniProt ID:P42830
mRNA ID:NM_002994
Length:114
RefSeq Status:
MSLLSSRAARVPGPSSSLCALLVLLLLLTQPGPIASAGPAAAVLRELRCVCLQTTQGVHPKMISNLQVFAIGPQCSKVEVVASLKNGKEICLDPEAPFLK
KVIQKILDGGNKEN
 
sig_peptide: 1..36
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3633
peptide sequence: 
MSLLSSRAARVPGPSSSLCALLVLLLLLTQPGPIAS

mat_peptide: 37..114
product: C-X-C motif chemokine 5
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P42830.1)
calculated_mol_wt: 8357
peptide sequence: 
AGPAAAVLRELRCVCLQTTQGVHPKMISNLQVFAIGPQCSKVEVVASLKNGKEICLDPEAPFLKKVIQKILDGGNKEN

mat_peptide: 44..114
product: ENA-78(8-78)
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P42830.1)
calculated_mol_wt: 7819
peptide sequence: 
LRELRCVCLQTTQGVHPKMISNLQVFAIGPQCSKVEVVASLKNGKEICLDPEAPFLKKVIQKILDGGNKEN

mat_peptide: 45..114
product: ENA-78(9-78)
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P42830.1)
calculated_mol_wt: 7706
peptide sequence: 
RELRCVCLQTTQGVHPKMISNLQVFAIGPQCSKVEVVASLKNGKEICLDPEAPFLKKVIQKILDGGNKEN
 
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