MGP Database

MGP002846

Ontology/Pathway Information

Entrez Gene ID	6507
Gene Name	solute carrier family 1 (glial high affinity glutamate transporter), member 3
Gene Symbol	SLC1A3
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0042995	IEA:Ensembl	C	cell projection
GO:0009986	IEA:Ensembl	C	cell surface
GO:0043205	IEA:Ensembl	C	fibril
GO:0016021	IEA:UniProtKB-KW	C	integral component of membrane
GO:0016020	TAS:ProtInc	C	membrane
GO:0043025	IEA:Ensembl	C	neuronal cell body
GO:0005886	TAS:Reactome	C	plasma membrane
GO:0016595	IEA:Ensembl	F	glutamate binding
GO:0005314	IEA:Ensembl	F	high-affinity glutamate transmembrane transporter activity
GO:0005313	IDA:BHF-UCL	F	L-glutamate transmembrane transporter activity
GO:0017153	IEA:InterPro	F	sodium:dicarboxylate symporter activity
GO:0031223	IEA:Ensembl	P	auditory behavior
GO:0048667	IEA:Ensembl	P	cell morphogenesis involved in neuron differentiation
GO:0021545	IEA:Ensembl	P	cranial nerve development
GO:0070779	IDA:UniProtKB	P	D-aspartate import
GO:0009449	IEA:Ensembl	P	gamma-aminobutyric acid biosynthetic process
GO:0006537	IEA:Ensembl	P	glutamate biosynthetic process
GO:0006811	TAS:Reactome	P	ion transport
GO:0051938	IDA:UniProtKB	P	L-glutamate import
GO:0089711	IDA:GOC	P	L-glutamate transmembrane transport
GO:0050885	IEA:Ensembl	P	neuromuscular process controlling balance
GO:0001504	TAS:ProtInc	P	neurotransmitter uptake
GO:0050806	IEA:Ensembl	P	positive regulation of synaptic transmission
GO:0046677	IEA:Ensembl	P	response to antibiotic
GO:0042493	IEA:Ensembl	P	response to drug
GO:0009416	IEA:Ensembl	P	response to light stimulus
GO:0009611	IEA:Ensembl	P	response to wounding
GO:0007605	IEA:Ensembl	P	sensory perception of sound
GO:0007268	TAS:ProtInc	P	synaptic transmission
GO:0055085	TAS:Reactome	P	transmembrane transport

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_13639	Astrocytic Glutamate-Glutamine Uptake And Metabolism
REACT_13685	Neuronal System
REACT_13594	Neurotransmitter uptake and Metabolism In Glial Cells
REACT_19118	SLC-mediated transmembrane transport
REACT_15518	Transmembrane transport of small molecules
REACT_13477	Transmission across Chemical Synapses
REACT_19397	Transport of inorganic cations/anions and amino acids/oligopeptides