MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP002856

UniProt Annotations

Entry Information
Gene Namesolute carrier family 2 (facilitated glucose/fructose transporter), member 5
Protein EntryGTR5_HUMAN
UniProt IDP22732
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=P22732-1; Sequence=Displayed; Name=2; IsoId=P22732-2; Sequence=VSP_042031;
FunctionCytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter.
InductionBy forskolin in Caco-2 cells. {ECO:0000269|PubMed:8037665}.
Mass SpectrometryMass=54973.98; Method=MALDI; Range=1-501; Evidence={ECO:0000269|PubMed:11840567};
Sequence CautionSequence=AAB60641.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityBelongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. {ECO:0000305}.
Subcellular LocationApical cell membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Membrane; Multi-pass membrane protein. Note=Localized on the apical membrane of the small intestine and the proximal tubule of the kidney. {ECO:0000250}.
Tissue SpecificityExpressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue.
  logo