MGP Database

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MGP002876

UniProt Annotations

Entry Information
Gene Namesolute carrier family 7 (cationic amino acid transporter, y+ system), member 1
Protein EntryCTR1_HUMAN
UniProt IDP30825
SpeciesHuman
Comments
Comment typeDescription
FunctionHigh-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. May also function as an ecotropic retroviral leukemia receptor. {ECO:0000269|PubMed:10485994}.
SimilarityBelongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family. {ECO:0000305}.
Subcellular LocationCell membrane {ECO:0000269|PubMed:10485994}; Multi-pass membrane protein {ECO:0000303|PubMed:10485994}.
Tissue SpecificityUbiquitous. {ECO:0000269|PubMed:1718082}.
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