MGP Database

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MGP002890

Ontology/Pathway Information

Entrez Gene ID6559
Gene Namesolute carrier family 12 (sodium/chloride transporter), member 3
Gene Symbol SLC12A3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016324 ISS:UniProtKBCapical plasma membrane
GO:0005829 IEA:EnsemblCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0016020 TAS:ProtIncCmembrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0015378 TAS:ProtIncFsodium:chloride symporter activity
GO:0005215 ISS:UniProtKBFtransporter activity
GO:1902476 TAS:GOCPchloride transmembrane transport
GO:0006821 TAS:GOCPchloride transport
GO:0006811 TAS:ReactomePion transport
GO:0035725 ISS:BHF-UCLPsodium ion transmembrane transport
GO:0006814 ISS:UniProtKBPsodium ion transport
GO:0055085 TAS:ReactomePtransmembrane transport
GO:0006810 TAS:ProtIncPtransport
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_19315Cation-coupled Chloride cotransporters
REACT_19118SLC-mediated transmembrane transport
REACT_15518Transmembrane transport of small molecules
REACT_19397Transport of inorganic cations/anions and amino acids/oligopeptides
SMP Pathway Links
SMP IDDescription
SMP00133Amiloride Action Pathway
SMP00090Bendroflumethiazide Action Pathway
SMP00583Blue diaper syndrome
SMP00088Bumetanide Action Pathway
SMP00078Chlorothiazide Action Pathway
SMP00122Chlorthalidone Action Pathway
SMP00103Cyclothiazide Action Pathway
SMP00723Cystinuria
SMP00135Eplerenone Action Pathway
SMP00097Ethacrynic Acid Action Pathway
SMP00115Furosemide Action Pathway
SMP00245Glucose Transporter Defect (SGLT2)
SMP00189Hartnup Disorder
SMP00100Hydrochlorothiazide Action Pathway
SMP00108Hydroflumethiazide Action Pathway
SMP00193Iminoglycinuria
SMP00584Iminoglycinuria
SMP00110Indapamide Action Pathway
SMP00483Kidney Function
SMP00197Lysinuric Protein Intolerance
SMP00585Lysinuric protein intolerance (LPI)
SMP00081Methyclothiazide Action Pathway
SMP00105Metolazone Action Pathway
SMP00080Polythiazide Action Pathway
SMP00091Quinethazone Action Pathway
SMP00184Renal Glucosuria
SMP00134Spironolactone Action Pathway
SMP00118Torsemide Action Pathway
SMP00132Triamterene Action Pathway
SMP00121Trichlormethiazide Action Pathway
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