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MGP002897

UniProt Annotations

Entry Information
Gene Namesolute carrier family 17 (organic anion transporter), member 1
Protein EntryNPT1_HUMAN
UniProt IDQ14916
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q14916-1; Sequence=Displayed; Name=2; IsoId=Q14916-2; Sequence=VSP_035012; Note=No experimental confirmation available.;
CautionIt is uncertain whether Met-1 or Met-3 is the initiator. {ECO:0000305}.
FunctionImportant for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane.
Sequence CautionSequence=BAA05888.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI19543.1; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the major facilitator superfamily. Sodium/anion cotransporter family. {ECO:0000305}.
Subcellular LocationMembrane; Multi-pass membrane protein.
SubunitInteracts with PDZK1. {ECO:0000250}.
Tissue SpecificityExpressed in kidney cortex, liver and brain but not in other tissues.
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