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MGP002920

Record overview

MGPD IDMGP002920
Gene ID6603
SpeciesHomo sapiens (Human)
Gene NameSWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
Gene Symbol SMARCD2
SynonymsRsc6p; BAF60B; CRACD2; PRO2451;
Alternate namesSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2; 60 kDa BRG-1/Brm-associated factor subunit B; BRG1-associated factor 60B; SWI/SNF complex 60 kDa subunit B; Swp73-like protein; chromatin remodeling complex BAF60B subunit; mammalian chromatin remodeling complex BRG1-associated factor 60B;
Chromosome17
Map Location17q23.3
SummaryThe protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for SMARCD2

Proteins

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2
Refseq ID:NP_001091896
Protein GI:148536864
UniProt ID:Q92925
mRNA ID:NM_001098426
Length:531
RefSeq Status:
MSGRGAGGFPLPPLSPGGGAVAAALGAPPPPAGPGMLPGPALRGPGPAGGVGGPGAAAFRPMGPAGPAAQYQRPGMSPGNRMPMAGLQVGPPAGSPFGAA
APLRPGMPPTMMDPFRKRLLVPQAQPPMPAQRRGLKRRKMADKVLPQRIRELVPESQAYMDLLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISN
TFSPSKAEGDSAGTAGTPGGTPAGDKVASWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKELYGPDNHLVEWHRMPTTQETDGFQVKRPGDLNVKCTL
LLMLDHQPPQYKLDPRLARLLGVHTQTRAAIMQALWLYIKHNQLQDGHEREYINCNRYFRQIFSCGRLRFSEIPMKLAGLLQHPDPIVINHVISVDPNDQ
KKTACYDIDVEVDDPLKAQMSNFLASTTNQQEIASLDVKIHETIESINQLKTQRDFMLSFSTDPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQ
PWAQEAVGRHIFAKVQQRRQELEQVLGIRLT
 
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