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MGP002948

Record overview

MGPD IDMGP002948
Gene ID6645
SpeciesHomo sapiens (Human)
Gene Namesyntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
Gene Symbol SNTB2
SynonymsSNT3; SNTL; SNT2B2; EST25263; D16S2531E;
Alternate namesbeta-2-syntrophin; 59 kDa dystrophin-associated protein A1 basic component 2; dystrophin-associated protein A1, 59kD, basic component 2; syntrophin-3;
Chromosome16
Map Location16q22.1
SummaryDystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for SNTB2

Proteins

beta-2-syntrophin
Refseq ID:NP_006741
Protein GI:5803177
UniProt ID:Q13425
mRNA ID:NM_006750
Length:540
RefSeq Status:
MRVAAATAAAGAGPAMAVWTRATKAGLVELLLRERWVRVVAELSGESLSLTGDAAAAELEPALGPAAAAFNGLPNGGGAGDSLPGSPSRGLGPPSPPAPP
RGPAGEAGASPPVRRVRVVKQEAGGLGISIKGGRENRMPILISKIFPGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRAGKEVLLEVKFIREV
TPYIKKPSLVSDLPWEGAAPQSPSFSGSEDSGSPKHQNSTKDRKIIPLKMCFAARNLSMPDLENRLIELHSPDSRNTLILRCKDTATAHSWFVAIHTNIM
ALLPQVLAELNAMLGATSTAGGSKEVKHIAWLAEQAKLDGGRQQWRPVLMAVTEKDLLLYDCMPWTRDAWASPCHSYPLVATRLVHSGSGCRSPSLGSDL
TFATRTGSRQGIEMHLFRVETHRDLSSWTRILVQGCHAAAELIKEVSLGCMLNGQEVRLTIHYENGFTISRENGGSSSILYRYPFERLKMSADDGIRNLY
LDFGGPEGELTMDLHSCPKPIVFVLHTFLSAKVTRMGLLV
 
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