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MGP002978

Record overview

MGPD IDMGP002978
Gene ID6723
SpeciesHomo sapiens (Human)
Gene Namespermidine synthase
Gene Symbol SRM
SynonymsPAPT; SPS1; SPDSY; SRML1;
Alternate namesspermidine synthase; putrescine aminopropyltransferase; spermidine synthase-1;
Chromosome1
Map Location1p36-p22
EC Number2.5.1.16
SummaryThe polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for SRM

Proteins

spermidine synthase
Refseq ID:NP_003123
Protein GI:63253298
UniProt ID:P19623
mRNA ID:NM_003132
Length:302
RefSeq Status:
MEPGPDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLII
GGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKED
GVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALND
VS
 
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